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Science & Medicine

François Jacob

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Who

François Jacob · Science & Medicine

What

Awarded the 1965 Nobel Prize for discovering the operon model of gene regulation.

When

17 June 1920, Nancy — 19 April 2013, Paris

Where

Nancy, Paris

Biography

François Jacob is recognized among Jewish contributors to Science & Medicine — Awarded the 1965 Nobel Prize for discovering the operon model of gene regulation.

How & why

Origins and early life

François Jacob (1920-2013) was born in Nancy, the only child of Simon Jacob, a merchant, and Thérèse Franck; his mother and the family around him were secular Jews, and shortly after his bar mitzvah he became an atheist.

Work and career

For his work in the French Resistance he received the Cross of Liberation, the Légion d'honneur and the Croix de guerre. With Jacques Monod he originated the idea that the level of enzymes in a cell is governed by the regulation of transcription: their 1961 work on the lactose system of the bacterium Escherichia coli — the operon model — showed how genes are switched on and off, one of the founding results of molecular biology.

Recognition

Jacob, Monod and André Lwoff shared the 1965 Nobel Prize in Physiology or Medicine for their discoveries concerning the genetic control of enzyme and virus synthesis. Jacob also wrote for the general public, and in 1994 received the inaugural Lewis Thomas Prize, which honours the scientist as poet.

Sources & external links

Verify and go deeper with these external references.

Source: Jinfo.org — Jews in Biology

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Contributions & Sources

Awarded the 1965 Nobel Prize for discovering the operon model of gene regulation.

1920

Source: Jinfo.org — Jews in Biology