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Science & Medicine

Adrian Krainer

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Who

Adrian Krainer · Science & Medicine

What

Developed the first drug for spinal muscular atrophy (nusinersen); Wolf Prize in Medicine (2021)

When

1958, Montevideo, Uruguay

Where

Uruguay · United States (Cold Spring Harbor Laboratory, New York)

Biography

Adrian Krainer is recognized among Jewish contributors to Science & Medicine — Developed the first drug for spinal muscular atrophy (nusinersen); Wolf Prize in Medicine (2021)

How & why

Born to a Jewish family of Hungarian and Romanian descent in Montevideo, Krainer spent decades studying how cells splice RNA and then applied that knowledge to disease. Working with Ionis, he designed nusinersen (Spinraza), an antisense drug that corrects splicing of the SMN2 gene and became the first approved treatment for spinal muscular atrophy. He received the Wolf Prize in Medicine in 2021.

Sources & external links

Verify and go deeper with these external references.

Source: Jinfo.org — Jewish recipients of the Wolf Prize (Medicine)

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Contributions & Sources

Developed the first drug for spinal muscular atrophy (nusinersen); Wolf Prize in Medicine (2021)

2021

Source: Jinfo.org — Jewish recipients of the Wolf Prize (Medicine)