Irwin Rose
Irwin Rose · Science & Medicine
Awarded the 2004 Nobel Prize for the discovery of ubiquitin-mediated protein degradation.
1926, Brooklyn, New York, United States — 2015, Deerfield, Massachusetts, United States
United States
Irwin Rose is recognized among Jewish contributors to Science & Medicine — Awarded the 2004 Nobel Prize for the discovery of ubiquitin-mediated protein degradation.
Born to a Jewish family in Brooklyn, Rose worked with Aaron Ciechanover and Avram Hershko to uncover how cells tag unwanted proteins for destruction: the small protein ubiquitin acts as a molecular label marking proteins for breakdown by the proteasome. This ubiquitin-mediated degradation system governs quality control and the cell cycle, and its failure is implicated in cancer and other diseases. The work earned the 2004 Nobel Prize in Chemistry.
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Source: Jinfo.org — Jews in Biology
Awarded the 2004 Nobel Prize for the discovery of ubiquitin-mediated protein degradation.
Source: Jinfo.org — Jews in Biology
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