DK
Science & Medicine

Daniel Koshland

Who

Daniel Koshland · Science & Medicine

What

Proposed the induced-fit model of enzyme action; National Medal of Science (1990)

When

1920, New York City, USA — 2007, USA

Where

USA

Biography

Daniel Koshland is recognized among Jewish contributors to Science & Medicine — Proposed the induced-fit model of enzyme action; National Medal of Science (1990)

How & why

Koshland was a biochemist at UC Berkeley who proposed the induced-fit model of enzyme action, showing that an enzyme changes shape to accommodate its substrate rather than fitting it rigidly like a lock and key, transforming understanding of catalysis and regulation. He later served as editor-in-chief of Science and received the National Medal of Science in 1990. He was born into a prominent Jewish family (the Koshland and Haas families of Levi Strauss & Co.).

Sources & external links

Verify and go deeper with these external references.

Source: Jinfo.org — Jewish recipients of the US National Medal of Science

Contributions & Sources

Proposed the induced-fit model of enzyme action; National Medal of Science (1990)

1990

Source: Jinfo.org — Jewish recipients of the US National Medal of Science