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Science & Medicine

Bert Vogelstein

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Who

Bert Vogelstein · Science & Medicine

What

Cancer geneticist who mapped the genetic mutations driving colorectal cancer progression.

When

1949, Baltimore, Maryland, USA

Where

United States (Baltimore, Maryland)

Biography

Bert Vogelstein is recognized among Jewish contributors to Science & Medicine — Cancer geneticist who mapped the genetic mutations driving colorectal cancer progression.

How & why

Vogelstein, from a Jewish family, is a cancer geneticist at Johns Hopkins. He mapped the sequence of genetic mutations — in genes such as APC, KRAS and TP53 — that turn normal colon cells into cancer, establishing the model of cancer as a stepwise accumulation of DNA changes. Among the most-cited scientists in the world, his framework reshaped cancer research and early-detection strategies.

Sources & external links

Verify and go deeper with these external references.

Source: Jinfo.org — Jews in Biology

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Contributions & Sources

Cancer geneticist who mapped the genetic mutations driving colorectal cancer progression.

1949

Source: Jinfo.org — Jews in Biology