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Science & Medicine

Zelig Eshhar

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Who

Zelig Eshhar · Science & Medicine

What

Immunologist who invented the CAR-T cell, the basis of modern cancer immunotherapy.

When

1941, Petah Tikva, Mandatory Palestine — 2025, Israel

Where

Israel (Weizmann Institute of Science · Tel Aviv Sourasky Medical Center)

Biography

Zelig Eshhar is recognized among Jewish contributors to Science & Medicine — Immunologist who invented the CAR-T cell, the basis of modern cancer immunotherapy.

How & why

Eshhar, an Israeli immunologist born Zelig Lipka in Petah Tikva, invented in the late 1980s at the Weizmann Institute the chimeric antigen receptor — fusing an antibody's target-recognition region to T-cell signalling machinery so that a patient's own T cells can be aimed at cancer. His 'T-body' concept is the direct basis of today's CAR-T therapies, among the most powerful cancer immunotherapies. He was widely honoured as a father of the field.

Sources & external links

Verify and go deeper with these external references.

Source: Jinfo.org — Jews in Biology

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Contributions & Sources

Immunologist who invented the CAR-T cell, the basis of modern cancer immunotherapy.

1941

Source: Jinfo.org — Jews in Biology