AH
Science & Medicine

Arthur Horwich

Who

Arthur Horwich · Science & Medicine

What

Biologist who discovered chaperonins, the cellular machines that fold proteins.

When

1951, United States

Where

United States (Yale School of Medicine)

Biography

Arthur Horwich is recognized among Jewish contributors to Science & Medicine — Biologist who discovered chaperonins, the cellular machines that fold proteins.

How & why

Horwich, a biologist and physician at Yale, discovered in 1989 that proteins do not always fold unaided: he identified the chaperonins, barrel-shaped molecular machines that provide a protected chamber in which newly made proteins fold correctly. This overturned the textbook view of protein folding and illuminated diseases of misfolding, earning him the Lasker, Shaw and Breakthrough prizes. Horwich appears in specialist indexes of Jewish scientists; his published biographies describe his Chicago upbringing but do not detail his background.

Sources & external links

Verify and go deeper with these external references.

Source: Jinfo.org — Jews in Biology

Contributions & Sources

Biologist who discovered chaperonins, the cellular machines that fold proteins.

1951

Source: Jinfo.org — Jews in Biology