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Science & Medicine

Jon Wolff

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Who

Jon Wolff · Science & Medicine

What

Gene-therapy researcher, pioneer of naked-DNA gene transfer

When

1956, Bayside, Queens, New York, USA — 2020, Denver, Colorado, USA

Where

United States

Biography

Jon Wolff is recognized among Jewish contributors to Science & Medicine — Gene-therapy researcher, pioneer of naked-DNA gene transfer

How & why

Jon A. Wolff was an American physician-scientist and gene-therapy pioneer who, with colleagues at the University of Wisconsin, discovered that injecting 'naked' DNA (and later RNA) directly into muscle could make cells produce proteins — a landmark 1990 Science paper later credited as an early step toward mRNA vaccines. His work advanced gene delivery for muscle, liver and brain disorders. His Jewish heritage is documented in surveys of Jews in the biomedical sciences.

Sources & external links

Verify and go deeper with these external references.

Source: Jinfo.org — Jews in Biomedical Science

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Contributions & Sources

Gene-therapy researcher, pioneer of naked-DNA gene transfer

1956

Source: Jinfo.org — Jews in Biomedical Science